Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 1.266


Transcription factors associated with TLX1..3_NFIC{dimer}.p2:

Gene SymbolEntrez IDGene Name
TLX1 3195 T-cell leukemia homeobox 1
TLX3 30012 T-cell leukemia homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX3chr5_+_1707362870.353.9e-01Click!
TLX1chr10_+_1028910600.186.6e-01Click!


Activity profile for motif TLX1..3_NFIC{dimer}.p2.

activity profile for motif TLX1..3_NFIC{dimer}.p2


Sorted Z-values histogram for motif TLX1..3_NFIC{dimer}.p2

Sorted Z-values for motif TLX1..3_NFIC{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX1..3_NFIC{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_58251715 2.517 NM_001199506
 PHACTR3
phosphatase and actin regulator 3
chr1_-_153588789 2.195 NM_020672
 S100A14
S100 calcium binding protein A14
chr1_-_242612757 1.864 NM_001195811
NM_001195812
 PLD5

phospholipase D family, member 5

chr1_-_153363544 1.737 NM_002964
 S100A8
S100 calcium binding protein A8
chr18_-_74728677 1.485 MBP
myelin basic protein
chr11_-_71752099 1.185 NUMA1
nuclear mitotic apparatus protein 1
chr16_+_57662301 1.130 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
 GPR56




G protein-coupled receptor 56




chr4_-_84255895 1.126 NM_001199830
 HPSE
heparanase
chr22_-_39640956 1.100 NM_002608
 PDGFB
platelet-derived growth factor beta polypeptide
chr8_-_21988518 1.094 NM_005144
NM_018411
 HR

hairless homolog (mouse)

chr9_-_23821842 1.050 NM_001171195
 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr9_-_23821808 1.033 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_-_84256304 0.992 NM_001166498
NM_006665
 HPSE

heparanase

chr10_+_82173574 0.967 NM_001243778
NM_001243782
 C10orf58

chromosome 10 open reading frame 58

chr15_-_83621350 0.965 NM_004839
NM_199330
 HOMER2

homer homolog 2 (Drosophila)

chr6_-_39197225 0.961 NM_003740
 KCNK5
potassium channel, subfamily K, member 5
chr19_-_49258646 0.958 NM_000148
 FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr4_-_84255999 0.956 HPSE
heparanase
chr19_-_36004553 0.951 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
 DMKN






dermokine






chr21_+_46875402 0.916 NM_030582
 COL18A1
collagen, type XVIII, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
18.48 1.85e-02 GO:0048755 branching morphogenesis of a nerve

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.64 1.22e-02 GO:0005624 membrane fraction
1.62 2.03e-03 GO:0044421 extracellular region part
1.59 3.26e-02 GO:0005626 insoluble fraction
1.54 4.08e-03 GO:0031226 intrinsic to plasma membrane
1.53 5.42e-03 GO:0005887 integral to plasma membrane
1.44 2.85e-04 GO:0044459 plasma membrane part

Nothing significant found in function category.